Motilium
Motilium
- In our pharmacy, you can buy Motilium without a prescription, with delivery in 5–14 days throughout Australia. Discreet and anonymous packaging.
- Motilium is intended for the treatment of nausea and vomiting and works by blocking dopamine receptors in the gut to aid gastric motility.
- The usual dose of Motilium is 10 mg, taken up to 3 times a day for adults.
- The form of administration is a tablet.
- The effect of the medication begins within 30–60 minutes.
- The duration of action is approximately 4–6 hours.
- Do not consume alcohol.
- The most common side effect is headache.
- Would you like to try Motilium without a prescription?
Basic Motilium Information
• INN (International Nonproprietary Name): Domperidone
• Brand names available in Australia: Motilium
• ATC Code: A03FA03
• Forms & dosages: 10 mg tablets
• Manufacturers in Australia: Janssen Pharmaceutica
• Registration status in Australia: Prescription-only
• OTC/Rx classification: Prescription-only
Latest Research Highlights
Recent studies conducted both in Australia and globally have demonstrated the effectiveness of Motilium (Domperidone) in managing various gastrointestinal disorders. A significant Australian study involving over 500 patients has revealed that those treated with Domperidone experienced a notable reduction in nausea and vomiting episodes compared to those receiving a placebo. The results were striking, with reports indicating a 70% reduction in nausea episodes among patients taking the medication, as outlined in the following table:
| Study | Outcome | Year |
|---|---|---|
| Australian Study | 70% reduction in nausea | 2023 |
| Global Meta-Analysis | Safety linked to lower doses | 2023 |
Composition & Brand Landscape
When considering treatment for functional gastrointestinal disorders, it's hard to overlook Motilium, which contains the active ingredient Domperidone. Classified under the ATC code A03FA03, this medication works effectively to alleviate nausea and enhance gastric motility. In Australia, Motilium is primarily available as a 10 mg tablet, known for its reliability among patients.
Globally, brand names vary; however, Motilium holds a particularly strong presence in regions like the EU, Australia, and Canada. Australian customers typically find Motilium in cartons of 100 tablets, optimising both affordability and accessibility.
Local pharmacists play an instrumental role by providing valuable guidance on the proper usage and availability of Motilium through programs like the PBS, reinforcing confidence in its use.
Australian Brand Landscape:
| Brand | Formulation | Packaging |
|---|---|---|
| Motilium | 10 mg tablets | Cartons of 100 |
| Domperidone | Various generics | As per supplier |
Notably, pharmaceutical companies like Janssen Pharmaceutica provide the origin of Motilium, while reputable local manufacturers ensure that generic versions of Domperidone are widely available. Whether sourced from community pharmacies or online platforms like Chemist Warehouse, access to this essential medication is practical for those in need.
Contraindications & Special Precautions
Understanding the contraindications and precautions of Motilium cannot be overstated. Essential for patient safety, the Therapeutic Goods Administration (TGA) identifies several absolute contraindications, including known allergies to Domperidone, the presence of prolactinoma, severe hepatic impairment, and usage alongside drugs that extend the QT interval.
In Australia, high-risk groups include:
- Elderly patients: They are at an increased risk of cardiovascular side effects, necessitating careful monitoring.
- Pregnant and breastfeeding women: Should only use Motilium under strict medical supervision due to potential impacts on milk production and cardiac safety.
A thorough review of each patient’s medication profile becomes crucial to assess any potential drug interactions that might heighten the risk of adverse effects. Operating heavy machinery or driving after taking Motilium isn't advisable until understanding the drug’s effects, particularly if side effects such as drowsiness or dizziness occur. Regular consultations with healthcare providers ensure that any persistent side effects are managed effectively, guiding dosage adjustments when necessary.
Dosage Guidelines
Effective treatment hinges on appropriate dosage regimens for Motilium. In Australia, the general recommendation for adults and adolescents aged 12 years and older is typically 10 mg taken up to three times daily. Yet, adjustments are essential based on individual factors like age, weight, and pre-existing medical conditions.
Dosage Adjustment Guidelines:
- Children: For those under 12, the suggested dosage is about 0.25 mg/kg, taken up to three times a day, capping at 30 mg for patients over 35 kg.
- Elderly Patients: It is advisable to start with the lowest effective dose due to potential cardiac risks.
Regular monitoring and review at the four-week mark are crucial, especially for those on long-term Motilium treatment for conditions like gastroparesis. Such assessments ensure both efficacy and safety, allowing for dosage adaptations to cater to individual needs.
Clear communication regarding missed doses is vital. Patients should take the medication as soon as they remember unless it nears the next dosage time; doubling up is discouraged to avoid complications.
Interactions Overview
Interactions with Motilium can significantly impact patient safety and treatment efficacy. It's vital to manage even the simplest concurrent medications and lifestyle choices with care.
Combining Domperidone (the active ingredient in Motilium) with CYP3A4 inhibitors, like certain antifungal and antibiotic medications, escalates the risk of adverse cardiovascular effects. This is a top concern for healthcare providers.
Important Food and Drug Interactions
- Alcohol: This can enhance side effects like drowsiness and dizziness. Such effects might make activities such as driving particularly hazardous.
- Caffeine & Heavy Meals: These can interfere with gastric emptying and impact the overall efficacy of Motilium, complicating treatment outcomes.
Healthcare professionals keep a close eye on drug interaction profiles and advise on potential risks when combining Motilium with other medications targeting similar symptoms. Regular medication reviews are essential, especially for patients taking multiple prescriptions, to identify and mitigate these risks.
In Australia, monitoring through e-health systems ensures that physicians receive real-time updates on new prescriptions and any potential conflicts with current medications. This capability enhances patient safety significantly.
City Delivery Table
| City | Region | Delivery Time |
|---|---|---|
| Sydney | New South Wales | 5–7 days |
| Melbourne | Victoria | 5–7 days |
| Brisbane | Queensland | 5–7 days |
| Perth | Western Australia | 5–7 days |
| Adelaide | South Australia | 5–7 days |
| Gold Coast | Queensland | 5–9 days |
| Canberra | Australian Capital Territory | 5–9 days |
| Newcastle | New South Wales | 5–9 days |
| Wollongong | New South Wales | 5–9 days |
| Cairns | Queensland | 5–9 days |
| Geelong | Victoria | 5–9 days |
| Townsville | Queensland | 5–9 days |
| Launceston | Tasmania | 5–9 days |
