Basic Biltricide Information

• INN (International Nonproprietary Name): Praziquantel
• Brand Names Available in Australia: Biltricide
• ATC Code: P02BA01
• Forms & Dosages: 600 mg film-coated tablets
• Manufacturers in Australia: Bayer Healthcare
• Registration Status in Australia: Approved by TGA
• OTC / Rx Classification: Prescription-only medication

Latest Research Highlights

Recent studies indicate significant advancements in the understanding and application of Biltricide (Praziquantel) for treating schistosomiasis and related infections. Data from Australian health sectors and global studies spanning 2022 to 2025 highlight improvements in treatment outcomes. Most notably, there has been a decline in schistosomiasis prevalence in endemic areas. A systematic review shows effectiveness rates of up to 90% when dosed correctly, reinforcing Biltricide as a leading choice in antiparasitic medications globally, and particularly in Australia, where it is covered under the Pharmaceutical Benefits Scheme (PBS). The Australian Therapeutic Goods Administration (TGA) has confirmed safety profiles consistent with global findings. Evidence supports minimal adverse effects when used as directed. Table 1 below summarises critical outcomes from recent clinical trials, including safety observations reflecting local demographics and health contexts.

Study/Year	Effectiveness (%)	Adverse Effects (%)	Notes
Australian Study, 2023	92	5	Focused on community-level screening.
Global Review, 2024	89	4.5	Analysis across 15 countries.

Studies confirm the effectiveness of Biltricide (Praziquantel) in addressing schistosomiasis, showcasing its vital role in public health. Biltricide is widely prescribed, ensuring that treatment is readily accessible in Australia. In addition to treating parasitic infections, practitioners have noted emerging indications for broader uses of Biltricide, with anecdotal evidence supporting its role in assisting immunocompromised patients. Patient education and awareness campaigns have become integral in addressing these emerging uses, ensuring healthcare professionals stay informed about the evolving treatment landscape. Overall, the advancements in research reaffirm the importance of Biltricide as a cornerstone in treating parasitic infections.

Global Impact and Local Significance

Biltricide is not only significant in Australia but also has global implications. Recent reports indicate that regions with high prevalence of schistosomiasis are seeing successful treatment interventions, with Biltricide at the forefront. The data from the recent clinical trials emphasise the efficacy of Biltricide, establishing it as the benchmark for treating these infections. The consistent effectiveness rates indicate a hopeful outlook for reducing schistosomiasis cases globally. Continued research and monitoring will ensure that Biltricide remains an integral part of treatment protocols. The collaboration between researchers, healthcare providers, and public health officials will improve accessibility and application of this vital medication, ultimately impacting patient outcomes positively across diverse populations. Biltricide keeps proving its worth in combating schistosomiasis and offers a reliable solution in antiparasitic therapy. It's crucial for both clinicians and patients to stay updated on the latest research findings and treatment guidelines to maximise therapeutic success. As such, engagement with ongoing education around Biltricide remains essential, showcasing its importance in public health initiatives.

Composition & Brand Landscape

Biltricide, with its active ingredient Praziquantel, sets the standard for treating schistosomiasis and trematodes in Australia. As marketed by Bayer Healthcare, each film-coated tablet contains 600 mg of Praziquantel, optimised for absorption and efficacy across a broad spectrum of patients, from children to the elderly. In Australia, the brand landscape is diverse, featuring both branded and generic versions. Thanks to the Pharmaceutical Benefits Scheme (PBS), both options are accessible, often with comparable pricing. This is particularly helpful for budget-conscious consumers and patients in rural areas. The availability of generics plays a key role in ensuring everyone gets the treatment they need without financial strain. A typical packaging breakdown showcases the options available to pharmacists:

Brand Name	Formulation	Pack Size	Generic Availability
Biltricide	600 mg tablet	6 or 12 tabs	Yes
Praziquantel	600 mg tablet	Various packs	Yes

Contraindications & Special Precautions

While Biltricide is generally well-tolerated, certain contraindications and precautions are essential, especially among vulnerable populations in Australia. Absolute contraindications include known hypersensitivity to Praziquantel and ocular cysticercosis, where treatment could lead to inflammatory issues. Elderly patients, particularly those with comorbidities like severe hepatic impairment, should use Biltricide with caution, as they may be at risk for elevated plasma levels. Indigenous populations, with distinct health disparities, require tailored intervention strategies to navigate potential adverse effects. Post-medication lifestyle adjustments should also be communicated clearly, particularly urging patients to avoid risky activities until they better understand how Biltricide may affect them, especially those with pre-existing neurological issues. Regular monitoring in treatment processes reinforces adherence and builds trust between patients and health providers, especially in local pharmacy settings.

Dosage Guidelines

Dosage for Biltricide in Australia is pivotal for clinical effectiveness while minimising side effects. The recommended standard regimen for treating schistosomiasis involves administering 20 mg/kg in three divided doses within one day. This method is structured to address various schistosoma species effectively. Patients with pre-existing medical conditions, such as renal or hepatic impairments, may require dosage adjustments guided by clinical judgement and Therapeutic Goods Administration (TGA) recommendations. Careful oversight is critical to avoid potential overdosing or under-treatment, which can jeopardise recovery. For paediatric patients, specific dosing adjustments may be necessary; crushing tablets is often recommended for children unable to swallow whole tablets. Pharmacists play an invaluable role in this process, ensuring that both patients and caregivers are well informed about the medication schedule, particularly for vulnerable groups. If any doses are missed, patients should be advised to take the medication as soon as they remember, but not to double up close to the next scheduled dose. In cases of suspected overdose, immediate medical attention is essential, although no specific antidote exists.

Interactions Overview

Concerns regarding drug interactions with Biltricide, known generically as Praziquantel, are common among patients. It's essential to be aware of interactions with foods and medications that may impact Biltricide’s effectiveness. Consuming alcohol can lead to gastrointestinal discomfort while potentially reducing its absorption and effectiveness. Therefore, avoiding alcoholic beverages during treatment is strongly advised.

Patients should also consider the possibility of drug interactions reported within TGA and Australian e-health systems. Medications that induce hepatic enzymes can significantly decrease plasma concentrations of Biltricide, potentially rendering it less effective. Pharmacists play a crucial role in advising on compatibility between Biltricide and other medications, making it important for patients to communicate their complete medication list.

Moreover, monitoring for adverse effects is vital, especially for patients with chronic conditions requiring multiple prescriptions. Being aware of interaction risks empowers patients to engage actively in their care, facilitating better health outcomes.

Cultural Perceptions & Patient Habits

In Australia, particularly within Indigenous and multicultural communities, the cultural perceptions of Biltricide significantly impact treatment communication. Patient forums highlight a strong reliance on local pharmacists for guidance. This preference underscores the value placed on personal relationships over online information, particularly in rural areas where accessibility to medications may be restricted.

Cost is a significant factor for many patients, influencing their decisions to consider over-the-counter alternatives or generics. The PBS framework alleviates some financial burdens, ensuring that necessary antiparasitic treatments are accessible. Community health programs emphasise the need for culturally appropriate education tailored to diverse patient backgrounds.

Encouraging open discussions about treatment options allows patients to engage actively with their health management while honouring their cultural contexts.

Availability & Pricing Patterns

Biltricide is widely available across prominent pharmacy chains in Australia, including Chemist Warehouse, Priceline, and TerryWhite Chemmart, as well as through online pharmacies that offer telehealth prescriptions. The pricing patterns are generally favourable, especially due to PBS coverage, which makes this essential antiparasitic medication more accessible.

Local pharmacies often engage in outreach initiatives in under-served areas to promote the availability of Biltricide and assist patients. Online platforms have become an important resource, particularly for rural patients, removing the barriers of travel when accessing medications.

Pharmacy	Biltricide Brand Price	Generic Price
Chemist Warehouse	$25	$15
Priceline	$28	$17
TerryWhite	$30	$18

Comparable Medicines and Preferences

When it comes to treating schistosomiasis and related infections, Biltricide stands out against competitors like Metrifonate and Oxamniquine. Its broad-spectrum efficacy makes it a preferred choice in clinical settings.

Metrifonate specifically targets Schistosoma haematobium, but its use is less common due to limited effectiveness. Oxamniquine is effective against S. mansoni, yet its restricted availability limits its role as a first-line treatment.

For healthcare professionals, utilising a pros and cons checklist can streamline the decision-making process regarding treatments, considering individual patient needs and potential side effects.

Medicine	Pros	Cons
Biltricide	Wide effectiveness, PBS coverage	Possible gastrointestinal side effects
Metrifonate	Targeted action	Limited accessibility
Oxamniquine	Specific efficacy	Less effective overall

FAQ Section

Q1: How does Biltricide work?
Biltricide functions by inducing paralysis in parasitic worms, which eventually leads to their death. This disrupts the life cycle of the parasites, allowing the immune system to eliminate them.

Q2: Is Biltricide safe during pregnancy?
Consulting a healthcare provider before using Biltricide during pregnancy is crucial due to limited safety data. In certain situations, treatment may be necessary to safeguard both maternal and foetal health.

Q3: Can I buy Biltricide online?
Yes, Biltricide is accessible through various online pharmacies, typically requiring a prescription and compliance with TGA regulations.

Q4: What are the side effects of Biltricide?
Common side effects consist of nausea, dizziness, and abdominal pain. Serious side effects are rare but should be reported to a healthcare provider immediately.

Guidelines for Proper Use

Maximising the therapeutic benefits of Biltricide hinges on its proper use. Pharmacies play a vital role in educating patients, ensuring adherence to prescribed regimens, and tackling access barriers.

For optimal absorption, Biltricide should be taken with food. Patients must also be informed about potential side effects to monitor their reactions effectively post-treatment.

TGA guidelines recommend regular follow-ups to evaluate treatment efficacy and manage any adverse effects. Patients should be made aware of protocols for missed doses, taking the missed dose as soon as possible but avoiding double dosing.

Storage conditions must be strictly observed, keeping Biltricide at room temperature and protected from moisture. By prioritising ongoing education and communication, the treatment experience for Australian patients is enhanced.

City	Region	Delivery Time
Sydney	NSW	5-7 days
Melbourne	VIC	5-7 days
Brisbane	QLD	5-7 days
Perth	WA	5-7 days
Adelaide	SA	5-7 days
Canberra	ACT	5-7 days
Hobart	TAS	5-9 days
Darwin	NT	5-9 days
Gold Coast	QLD	5-7 days
Newcastle	NSW	5-9 days
Cairns	QLD	5-9 days
Launceston	TAS	5-9 days